Abstract Background The holistic approach of traditional medicine renders the identification of its mechanisms of action difficult.Microarray Massachusetts technology provides an efficient way to analyze the complex genome-wide gene expression of cells treated with mixtures of medicinal ingredients.We performed transcriptional profiling of MCF-7 ce
BackgroundCanine Leishmaniasis (CanL) caused by the L.infantum species is one of the biggest threats to the health of the South American canine population.Chemotherapeutics currently used for the treatment of CanL fail to induce a total parasite clearance while inducing numerous side effects.As CanL is an immunomodulated disease, the use of immuno-
BACKGROUND: Sequence analysis is a set of tools increasingly used in demography and other social sciences to analyse longitudinal categorical data.Typically, single (e.g., education trajectories) or multiple parallel temporal processes (e.g., work and family) are analysed by using crisp clustering algorithms that reduce complexity by partitioning c